Marios Gavrielatos

Marios Gavrielatos

Μάριος Γαβριελάτος · MAH-ree-os Gahv-ree-eh-LAH-tos
PhD Student Computational Biology CMU–Pitt CPCB

I am a PhD student in the Joint Carnegie Mellon University – University of Pittsburgh Computational Biology (CPCB) program, advised by Dr. David Koes. My research focuses on improving the synthesizability of molecules generated by deep generative models for computational drug discovery. I aim to create tools that advance research, contribute to open-source software, and help drive progress in personalized medicine.

Education

Department of Computational and Systems Biology, University of Pittsburgh

PhD Student in Computational Biology
Aug 2025 – Present

Department of Informatics, NKUA

MSc in Bioinformatics and Biomedical Data Science
Oct 2021 – Sep 2023

Department of Biology, NKUA

BSc in Biology
Sep 2016 – Sep 2020

Experience

Mayo Clinic

Special Project Associate — Bioinformatician
Sep 2023 – Aug 2025
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News

Milestones, publications, and updates throughout my journey.

Jan
2026
News

Joined Koes Lab

Officially joined Dr. David Koes' lab in the CMU–Pitt CPCB program, focusing on improving the synthesizability of molecules generated by deep generative models.

Sep
2025
Publication

New paper in npj Dementia

"Describing the diversity of MAPT transcripts in the parietal cortex of Pick's disease patients" published in npj Dementia.

Sep
2025
Challenge

Top finisher — Autoimmune Disease ML Challenge (Broad Institute)

Placed 5th in Crunch 1 and 3rd in Crunch 2 of the Autoimmune Disease Machine Learning Challenge hosted by the Eric and Wendy Schmidt Center.

Aug
2025
News

Joined the CMU–Pitt CPCB PhD Program

Started my PhD in Computational Biology in the Joint Carnegie Mellon – University of Pittsburgh program.

Nov
2025
Publication

Paper in Annals of Neurology

"Association between Human Leukocyte Antigen Alleles and Neuropathological Outcomes in Lewy Body Disease" published in Annals of Neurology.

May
2025
Publication

Paper in Science Advances

"Characterizing the expression profile of 3R tau pathology in Pick's disease" published in Science Advances.

2024
Publication

Paper in BioTech

"A Machine Learning-Based Web Tool for the Severity Prediction of COVID-19" published in BioTech 13 (3), 22.

2024
News

ELIDEK Research Funding

Our proposal was selected among 23 funded out of 278 submissions in Life Sciences by ELIDEK (Hellenic Foundation for Research & Innovation).

Sep
2023
News

Joined Mayo Clinic as Bioinformatician

Started as Special Project Associate II – Bioinformatician at Mayo Clinic, Jacksonville, FL, in the Ross Lab working on neurodegenerative disease research.

Sep
2023
News

Completed MSc in Bioinformatics & Biomedical Data Science

Graduated from the National and Kapodistrian University of Athens, Department of Informatics. Thesis on interpretable ML/DL methods for biomedical time series in the Manolakos Lab.

Mar
2023
Challenge

Won the Cancer Immunotherapy Data Science Grand Challenge

Won Challenge 1 of the Eric and Wendy Schmidt Center's Cancer Immunotherapy competition at the Broad Institute with teammate Konstantinos Kyriakidis.

Oct
2021
News

Started MSc in Bioinformatics & Biomedical Data Science

Enrolled in the MSc program at the National and Kapodistrian University of Athens, Department of Informatics.

2021
Publication

First publication in Molecular Medicine Reports

"Benchmarking of next and third generation sequencing technologies and their associated algorithms for de novo genome assembly" published in Molecular Medicine Reports 23 (4), 251.

Nov 2020
– 2021
News

Mandatory Military Service — Greek Navy

Served in the Hellenic Navy as part of mandatory military service in Greece.

Sep
2020
News

Completed BSc in Biology

Graduated from the National and Kapodistrian University of Athens, Department of Biology, with a focus on bioinformatics.

Jun 2019
– Sep 2020
News

BSc Thesis at BRFAA — Michalopoulos Lab

Conducted thesis research on benchmarking sequencing technologies for de novo genome assembly at the Biomedical Research Foundation of the Academy of Athens.

Sep
2016
News

Started BSc in Biology

Enrolled in the Department of Biology at the National and Kapodistrian University of Athens.

Background

Detailed affiliations, labs, and thesis work.

PhD Student in Computational Biology
University of Pittsburgh, Department of Computational and Systems Biology · Koes Lab
Aug 2025 – Present
Special Project Associate — Bioinformatician
Mayo Clinic, Jacksonville, FL · Ross Lab
Sep 2023 – Aug 2025
MSc Bioinformatics & Biomedical Data Science
National & Kapodistrian University of Athens, Department of Informatics
Oct 2021 – Sep 2023
↳ Thesis: Interpretable ML/DL methods for biomedical time series
NKUA, Department of Informatics · Manolakos Lab
Oct 2021 – Sep 2023
BSc in Biology, focus on Bioinformatics
National & Kapodistrian University of Athens, Department of Biology
Sep 2016 – Sep 2020
↳ Thesis: Benchmarking sequencing technologies for de novo genome assembly
Biomedical Research Foundation, Academy of Athens · Michalopoulos Lab
Jun 2019 – Sep 2020

Publications

Click on "View All Publications" for more details.

Association between Human Leukocyte Antigen Alleles and Neuropathological Outcomes in Lewy Body Disease

M. Gavrielatos, M.G. Heckman, A.I. Soto-Beasley, S.G. Blumenfeld, X. Hou, S. Koga, M.E. Murray, K. Kasanuki, D. Ono, F.C. Fiesel, ... D.W. Dickson, O.A. Ross

Annals of Neurology, November 2025

Paper Scholar

Describing the diversity of MAPT transcripts in the parietal cortex of Pick's disease patients

N. Tamvaka*, M.G. Stuber*, M. Gavrielatos, A.I. Soto-Beasley, M.G. Heckman, ... D.W. Dickson, O.A. Ross

npj Dementia 1 (1), 22, September 2025

Paper

Characterizing the expression profile of 3R tau pathology in Pick's disease

N. Tamvaka, A.I. Soto-Beasley, M. Gavrielatos, M.G. Heckman, Y. Ren, ... D.W. Dickson, O.A. Ross

Science Advances 11 (18), eadt6105, May 2025

Paper PMC

A Machine Learning-Based Web Tool for the Severity Prediction of COVID-19

A. Christodoulou, M.S. Katsarou, C. Emmanouil, M. Gavrielatos, D. Georgiou, ... I. Michalopoulos, N. Drakoulis

BioTech 13 (3), 22, July 2024

Paper PMC

Benchmarking of next and third generation sequencing technologies and their associated algorithms for de novo genome assembly

M. Gavrielatos, K. Kyriakidis, D.A. Spandidos, I. Michalopoulos

Molecular Medicine Reports 23 (4), 251, February 2021

PubMed PMC
View All Publications →

Challenges

Machine learning competitions in computational biology and biomedicine.

Autoimmune Disease Machine Learning Challenge

5th — Crunch 1 3rd — Crunch 2

Built hybrid CNN+MLP models to predict spatial gene expression from histopathology images in inflammatory bowel disease. Enhanced embeddings from pretrained histopathology models for gene-level predictions and developed multi-channel architectures capturing local spatial relationships.

Eric and Wendy Schmidt Center & Klarman Cell Observatory, Broad Institute of MIT and Harvard · 2024–2025

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Cancer Immunotherapy Data Science Grand Challenge

🏆 1st Place — Challenge 1

Developed a novel deep learning model to predict T cell state transitions after gene knockouts, integrating single-cell data with biological pathway databases (Reactome, STRING). First ML competition entry — won by developing a completely new approach.

Eric and Wendy Schmidt Center, Broad Institute of MIT and Harvard · 2023

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Get in Touch

I'm always open to discussing research collaborations, computational biology, drug discovery, or just connecting! Don't hesitate to reach out!

mag1037@pitt.edu LinkedIn

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